Log InRegister
Quick Links : The Mindat ManualThe Rock H. Currier Digital LibraryMindat Newsletter [Free Download]
Home PageAbout MindatThe Mindat ManualHistory of MindatCopyright StatusWho We AreContact UsAdvertise on Mindat
Donate to MindatCorporate SponsorshipSponsor a PageSponsored PagesMindat AdvertisersAdvertise on Mindat
Learning CenterWhat is a mineral?The most common minerals on earthInformation for EducatorsMindat ArticlesThe ElementsThe Rock H. Currier Digital LibraryGeologic Time
Minerals by PropertiesMinerals by ChemistryAdvanced Locality SearchRandom MineralRandom LocalitySearch by minIDLocalities Near MeSearch ArticlesSearch GlossaryMore Search Options
Search For:
Mineral Name:
Locality Name:
Keyword(s):
 
The Mindat ManualAdd a New PhotoRate PhotosLocality Edit ReportCoordinate Completion ReportAdd Glossary Item
Mining CompaniesStatisticsUsersMineral MuseumsClubs & OrganizationsMineral Shows & EventsThe Mindat DirectoryDevice SettingsThe Mineral Quiz
Photo SearchPhoto GalleriesSearch by ColorNew Photos TodayNew Photos YesterdayMembers' Photo GalleriesPast Photo of the Day GalleryPhotography

Ma, Chao, Taghour, Mohammed S., Belal, Amany, Mehany, Ahmed B. M., Mostafa, Naglaa, Nabeeh, Ahmed, Eissa, Ibrahim H., Al-Karmalawy, Ahmed A. (2021) Design and Synthesis of New Quinoxaline Derivatives as Potential Histone Deacetylase Inhibitors Targeting Hepatocellular Carcinoma: In Silico, In Vitro, and SAR Studies. Frontiers in Chemistry, 9. doi:10.3389/fchem.2021.725135

Advanced
   -   Only viewable:
Reference TypeJournal (article/letter/editorial)
TitleDesign and Synthesis of New Quinoxaline Derivatives as Potential Histone Deacetylase Inhibitors Targeting Hepatocellular Carcinoma: In Silico, In Vitro, and SAR Studies
JournalFrontiers in Chemistry
AuthorsMa, ChaoAuthor
Taghour, Mohammed S.Author
Belal, AmanyAuthor
Mehany, Ahmed B. M.Author
Mostafa, NaglaaAuthor
Nabeeh, AhmedAuthor
Eissa, Ibrahim H.Author
Al-Karmalawy, Ahmed A.Author
Year2021 (September 22)Volume9
PublisherFrontiers Media SA
DOIdoi:10.3389/fchem.2021.725135Search in ResearchGate
Generate Citation Formats
Mindat Ref. ID15661131Long-form Identifiermindat:1:5:15661131:4
GUID0
Full ReferenceMa, Chao, Taghour, Mohammed S., Belal, Amany, Mehany, Ahmed B. M., Mostafa, Naglaa, Nabeeh, Ahmed, Eissa, Ibrahim H., Al-Karmalawy, Ahmed A. (2021) Design and Synthesis of New Quinoxaline Derivatives as Potential Histone Deacetylase Inhibitors Targeting Hepatocellular Carcinoma: In Silico, In Vitro, and SAR Studies. Frontiers in Chemistry, 9. doi:10.3389/fchem.2021.725135
Plain TextMa, Chao, Taghour, Mohammed S., Belal, Amany, Mehany, Ahmed B. M., Mostafa, Naglaa, Nabeeh, Ahmed, Eissa, Ibrahim H., Al-Karmalawy, Ahmed A. (2021) Design and Synthesis of New Quinoxaline Derivatives as Potential Histone Deacetylase Inhibitors Targeting Hepatocellular Carcinoma: In Silico, In Vitro, and SAR Studies. Frontiers in Chemistry, 9. doi:10.3389/fchem.2021.725135
In(2022) Frontiers in Chemistry Vol. 9. Frontiers Media SA

See Also

These are possibly similar items as determined by title/reference text matching only.

Al-Karmalawy, Ahmed A., Dahab, Mohammed A., Metwaly, Ahmed M., Elhady, Sameh S., Elkaeed, Eslam B., Eissa, Ibrahim H., Darwish, Khaled M. (2021) Molecular Docking and Dynamics Simulation Revealed the Potential Inhibitory Activity of ACEIs Against SARS-CoV-2 Targeting the hACE2 Receptor. Frontiers in Chemistry, 9. doi:10.3389/fchem.2021.661230
Yousef, Reda G., Sakr, Helmy M., Eissa, Ibrahim H., Mehany, Ahmed. B. M., Metwaly, Ahmed M., Elhendawy, Mostafa A., Radwan, Mohamed M., ElSohly, Mahmoud A., Abulkhair, Hamada S., El-Adl, Khaled. (2021) New quinoxaline-2(1H)-ones as potential VEGFR-2 inhibitors: design, synthesis, molecular docking, ADMET profile and anti-proliferative evaluations. New Journal of Chemistry, 45 (36) 16949-16964 doi:10.1039/d1nj02509k
El-Metwally, Souad A., Omara, Mariam, Elkady, Hazem, Elkaeed, Eslam B., Al-ghulikah, Hanan A., Taghour, Mohammed S., El-Mahdy, Hesham A., Ibrahim, Ibrahim M., Husein, Dalal Z., Metwaly, Ahmed M., Eissa, Ibrahim H. (2024) New modified thieno[2,3-d]pyrimidine derivatives as VEGFR-2 inhibitors: Design, synthesis, in vitro anti-cancer evaluation and divers in silico studies. Journal of Molecular Structure, 1302. 137465 doi:10.1016/j.molstruc.2023.137465
Hamed, Mohammed I. A., Darwish, Khaled M., Soltane, Raya, Chrouda, Amani, Mostafa, Ahmed, Abo Shama, Noura M., Elhady, Sameh S., Abulkhair, Hamada S., Khodir, Ahmed E., Elmaaty, Ayman Abo, Al-karmalawy, Ahmed A. (2021) β-Blockers bearing hydroxyethylamine and hydroxyethylene as potential SARS-CoV-2 Mpro inhibitors: rational based design, in silico, in vitro, and SAR studies for lead optimization. RSC Advances, 11 (56) 35536-35558 doi:10.1039/d1ra04820a
Fayed, Eman A., Ammar, Yousry A., Saleh, Marwa A., Bayoumi, Ashraf H., Belal, Amany, Mehany, Ahmed B.M., Ragab, Ahmed (2021) Design, synthesis, antiproliferative evaluation, and molecular docking study of new quinoxaline derivatives as apoptotic inducers and EGFR inhibitors. Journal of Molecular Structure, 1236. 130317 doi:10.1016/j.molstruc.2021.130317
El-Metwally, Souad A., Abuelkhir, Abdelrahman A., Elkady, Hazem, Taghour, Mohammed S., Ibrahim, Ibrahim M., Husein, Dalal Z., Alsfouk, Aisha A., Sultan, Ahlam, Ismail, Ahmed, Elkhawaga, Samy Y., Elkaeed, Eslam B., Metwaly, Ahmed M., Eissa, Ibrahim H. (2023) In vitro and in silico evaluation of new thieno[2,3-d]pyrimidines as anti-cancer agents and apoptosis inducers targeting VEGFR-2. Computational Biology and Chemistry, 106. 107928 doi:10.1016/j.compbiolchem.2023.107928
Abdallah, Abdallah E., Alesawy, Mohamed S., Eissa, Sally I., El-Fakharany, Esmail M., Kalaba, Mohamed H., Sharaf, Mohamed H., Abo Shama, Noura M., Mahmoud, Sara H., Mostafa, Ahmed, Al-Karmalawy, Ahmed A., Elkady, Hazem (2021) Design and synthesis of new 4-(2-nitrophenoxy)benzamide derivatives as potential antiviral agents: molecular modeling and in vitro antiviral screening. New Journal of Chemistry, 45 (36) 16557-16571 doi:10.1039/d1nj02710g
Belal, Amany, Elballal, Mohammed S., Al-Karmalawy, Ahmed A., Hassan, Ahmed H. E., Roh, Eun Joo, Ghoneim, Mohammed M., Ali, Mohamed A. M., Obaidullah, Ahmad J., Alotaibi, Jawaher M., Shaaban, Salwa, Elanany, Mohamed A. (2024) Exploring the sedative properties of natural molecules from hop cones (Humulus lupulus) as promising natural anxiolytics through GABA receptors and the human serotonin transporter. Frontiers in Chemistry, 12. doi:10.3389/fchem.2024.1425485
Elmaaty, Ayman Abo, Eldehna, Wagdy M., Khattab, Muhammad, Kutkat, Omnia, Alnajjar, Radwan, El-Taweel, Ahmed N., Al-Rashood, Sara T., Abourehab, Mohammed A. S., Binjubair, Faizah A., Saleh, Mohamed A., Belal, Amany, Al-Karmalawy, Ahmed A. (2022) Anticoagulants as Potential SARS-CoV-2 Mpro Inhibitors for COVID-19 Patients: In Vitro, Molecular Docking, Molecular Dynamics, DFT, and SAR Studies. International Journal of Molecular Sciences, 23 (20) 12235 doi:10.3390/ijms232012235
Saleh, Abdulrahman M., Mahdy, Hazem A., El-Zahabi, Mohamed Ayman, Mehany, Ahmed B. M., Khalifa, Mohamed M., Eissa, Ibrahim H. (2023) Design, synthesis, in silico studies, and biological evaluation of novel pyrimidine-5-carbonitrile derivatives as potential anti-proliferative agents, VEGFR-2 inhibitors and apoptotic inducers. RSC Advances, 13 (32) Royal Society of Chemistry (RSC) 22122-22147 doi:10.1039/d3ra04182d
Belal, Amany, Abdou, Aly, Miski, Samar F., Ali, Mohamed A. M., Ghamry, Heba I., Obaidullah, Ahmad J., Zaky, Mohamed Y., Hassan, Ahmed H. E., Roh, Eun Joo, Al-Karmalawy, Ahmed A., et al. (2025) Exploring the potential of some natural indoles as antiviral agents: quantum chemical analysis, inverse molecular docking, and affinity calculations. Frontiers in Chemistry, 12. doi:10.3389/fchem.2024.1521298
 
and/or  
Mindat.org is an outreach project of the Hudson Institute of Mineralogy, a 501(c)(3) not-for-profit organization.
Copyright © mindat.org and the Hudson Institute of Mineralogy 1993-2025, except where stated. Most political location boundaries are © OpenStreetMap contributors. Mindat.org relies on the contributions of thousands of members and supporters. Founded in 2000 by Jolyon Ralph.
To cite: Ralph, J., Von Bargen, D., Martynov, P., Zhang, J., Que, X., Prabhu, A., Morrison, S. M., Li, W., Chen, W., & Ma, X. (2025). Mindat.org: The open access mineralogy database to accelerate data-intensive geoscience research. American Mineralogist, 110(6), 833–844. doi:10.2138/am-2024-9486.
Privacy Policy - Terms & Conditions - Contact Us / DMCA issues - Report a bug/vulnerability Current server date and time: August 28, 2025 04:00:39
Go to top of page