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Pokorski, Jonathan K., Witschi, Mark A., Purnell, Bethany L., Appella, Daniel H. (2004) (S,S)-trans-Cyclopentane-Constrained Peptide Nucleic Acids. A General Backbone Modification that Improves Binding Affinity and Sequence Specificity. Journal Of The American Chemical Society, 126 (46) 15067-15073 doi:10.1021/ja046280q

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Reference TypeJournal (article/letter/editorial)
Title(S,S)-trans-Cyclopentane-Constrained Peptide Nucleic Acids. A General Backbone Modification that Improves Binding Affinity and Sequence Specificity
JournalJournal Of The American Chemical Society
AuthorsPokorski, Jonathan K.Author
Witschi, Mark A.Author
Purnell, Bethany L.Author
Appella, Daniel H.Author
Year2004 (November)Volume126
Issue46
PublisherAmerican Chemical Society (ACS)
DOIdoi:10.1021/ja046280qSearch in ResearchGate
Generate Citation Formats
Mindat Ref. ID1639802Long-form Identifiermindat:1:5:1639802:5
GUID0
Full ReferencePokorski, Jonathan K., Witschi, Mark A., Purnell, Bethany L., Appella, Daniel H. (2004) (S,S)-trans-Cyclopentane-Constrained Peptide Nucleic Acids. A General Backbone Modification that Improves Binding Affinity and Sequence Specificity. Journal Of The American Chemical Society, 126 (46) 15067-15073 doi:10.1021/ja046280q
Plain TextPokorski, Jonathan K., Witschi, Mark A., Purnell, Bethany L., Appella, Daniel H. (2004) (S,S)-trans-Cyclopentane-Constrained Peptide Nucleic Acids. A General Backbone Modification that Improves Binding Affinity and Sequence Specificity. Journal Of The American Chemical Society, 126 (46) 15067-15073 doi:10.1021/ja046280q
In(2004, November) Journal Of The American Chemical Society Vol. 126 (46) American Chemical Society (ACS)

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Myers, Michael C., Pokorski, Jonathan K., Appella, Daniel H. (2004) Peptide Nucleic Acids with a Flexible Secondary Amine in the Backbone Maintain Oligonucleotide Binding Affinity. Organic Letters, 6. 4699-4702 doi:10.1021/ol0480980
Myers, Michael C., Witschi, Mark A., Larionova, Nataliya V., Franck, John M., Haynes, Russell D., Hara, Toshiaki, Grajkowski, Andrzej, Appella, Daniel H. (2003) A Cyclopentane Conformational Restraint for a Peptide Nucleic Acid:  Design, Asymmetric Synthesis, and Improved Binding Affinity to DNA and RNA. Organic Letters, 5. 2695-2698 doi:10.1021/ol0348811
Lawton, Graham R., Appella, Daniel H. (2004) Nonionic Side Chains Modulate the Affinity and Specificity of Binding between Functionalized Polyamines and Structured RNA. Journal Of The American Chemical Society, 126 (40) 12762-12763 doi:10.1021/ja046436m
Zheng, Hongchao, Saha, Mrinmoy, Appella, Daniel H. (2018) Synthesis of Fmoc-Protected (S,S)-trans-Cyclopentane Diamine Monomers Enables the Preparation and Study of Conformationally Restricted Peptide Nucleic Acids. Organic Letters, 20. 7637-7640 doi:10.1021/acs.orglett.8b03374
Englund, Ethan A., Xu, Qun, Witschi, Mark A., Appella, Daniel H. (2006) PNA−DNA Duplexes, Triplexes, and Quadruplexes Are Stabilized withtrans-Cyclopentane Units. Journal Of The American Chemical Society, 128 (51) 16456-16457 doi:10.1021/ja064317w
Micklitsch, Christopher M., Oquare, Bereket Yemane, Zhao, Chao, Appella, Daniel H. (2013) Cyclopentane-Peptide Nucleic Acids for Qualitative, Quantitative, and Repetitive Detection of Nucleic Acids. Analytical Chemistry, 85 (1). 251-257 doi:10.1021/ac3026459
Englund, Ethan A., Appella, Daniel H. (2005) Synthesis of γ-Substituted Peptide Nucleic Acids:  A New Place to Attach Fluorophores without Affecting DNA Binding. Organic Letters, 7. 3465-3467 doi:10.1021/ol051143z
Zhang, Ning, Appella, Daniel H. (2007) Colorimetric Detection of Anthrax DNA with a Peptide Nucleic Acid Sandwich-Hybridization Assay. Journal Of The American Chemical Society, 129 (27) 8424-8425 doi:10.1021/ja072744j
Carlson, Coby B., Beal, Peter A. (2002) Point of Attachment and Sequence of Immobilized Peptide-Acridine Conjugates Control Affinity for Nucleic Acids. Journal Of The American Chemical Society, 124 (29) 8510-8511 doi:10.1021/ja026029f
Mokhir, Andriy, Krämer, Roland, Wolf, Helena (2004) Zn2+-Dependent Peptide Nucleic Acids Probes. Journal Of The American Chemical Society, 126 (20) 6208-6209 doi:10.1021/ja0397613
Englund, Ethan A., Appella, Daniel H. (2007) γ-Substituted Peptide Nucleic Acids Constructed fromL-Lysine are a Versatile Scaffold for Multifunctional Display. Angewandte Chemie International Edition, 46 (9). 1414-1418 doi:10.1002/anie.200603483
 
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