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Meleiro, Marco; Henrique, Rui (2025) Epigenetic Alterations in Glioblastoma Multiforme as Novel Therapeutic Targets: A Scoping Review. International Journal of Molecular Sciences, 26 (12). doi:10.3390/ijms26125634

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Reference TypeJournal (article/letter/editorial)
TitleEpigenetic Alterations in Glioblastoma Multiforme as Novel Therapeutic Targets: A Scoping Review
JournalInternational Journal of Molecular Sciences
AuthorsMeleiro, MarcoAuthor
Henrique, RuiAuthor
Year2025 (June 12)Volume26
Issue12
PublisherMDPI AG
DOIdoi:10.3390/ijms26125634Search in ResearchGate
Generate Citation Formats
Mindat Ref. ID18569315Long-form Identifiermindat:1:5:18569315:2
GUID0
Full ReferenceMeleiro, Marco; Henrique, Rui (2025) Epigenetic Alterations in Glioblastoma Multiforme as Novel Therapeutic Targets: A Scoping Review. International Journal of Molecular Sciences, 26 (12). doi:10.3390/ijms26125634
Plain TextMeleiro, Marco; Henrique, Rui (2025) Epigenetic Alterations in Glioblastoma Multiforme as Novel Therapeutic Targets: A Scoping Review. International Journal of Molecular Sciences, 26 (12). doi:10.3390/ijms26125634
In(2025, June) International Journal of Molecular Sciences Vol. 26 (12). MDPI AG

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(2024, December 22). A Phase I Trial of Pembrolizumab and Vorinostat Combined with Temozolomide and Radiation Therapy for Newly Diagnosed Glioblastoma, Available online: https://clinicaltrials.gov/study/NCT03426891.
(2024, December 22). A Phase 1, Open-Label Study to Assess the Pharmacokinetics, Pharmacodynamics and Central Nervous System (CNS) Penetration of CC-90010 in Preoperative Subjects with Progressive or Recurrent Who Grade II Diffuse Astrocytoma, Grade III Anaplastic Astrocytoma and Recurrent Glioblastoma Scheduled for Resection, Available online: https://clinicaltrials.gov/study/NCT04047303.
Vieito (2022) Neurooncol. Adv. Trotabresib (CC-90010) in combination with adjuvant temozolomide or concomitant temozolomide plus radiotherapy in patients with newly diagnosed glioblastoma 4, vdac146
(2024, December 22). A Phase 1b/2 Study of FT-2102 in Patients with Advanced Solid Tumors and Gliomas with an IDH1 Mutation, Available online: https://clinicaltrials.gov/study/NCT03684811.
(2024, December 22). A Phase 1 Study of DS-1001b in Patients with IDH1 Mutated Gliomas, Available online: https://clinicaltrials.gov/study/NCT03030066.
Not Yet Imported: Molecular Cancer Therapeutics - journal-article : 10.1158/1535-7163.MCT-18-1349

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(2024, December 22). A Phase 0 First-In-Human Study Using NU-0129: A Spherical Nucleic Acid (SNA) Gold Nanoparticle Targeting BCL2L12 in Recurrent Glioblastoma Multiforme or Gliosarcoma Patients, Available online: https://clinicaltrials.gov/study/NCT03020017.
(2024, December 22). Establishment of a Signature of Circulating microRNA as a Tool to Aid Diagnosis of Primary Brain Tumors in Adults, Available online: https://clinicaltrials.gov/study/NCT03630861.
(2024, December 22). Improving Personalised Glioblastoma Care by Stem Cell Analysis, Omics (Including Immunomics) and Artificial Intelligence Approaches, Available online: https://clinicaltrials.gov/study/NCT05941234.
(2024, December 22). Monitoring of Patients with Diffuse Gliomas Using Circulating miRNAs, Available online: https://clinicaltrials.gov/study/NCT06203496.
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Wang (2016) Anticancer Res. Histone Methylation by Temozolomide; A Classic DNA Methylating Anticancer Drug 36, 3289
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Kroes (2016) Glycobiology The role of DNA methylation in ST6Gal1 expression in gliomas 26, 1271
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Jiang (2016) OncoTargets Ther. Knockdown of long noncoding RNA H19 sensitizes human glioma cells to temozolomide therapy 9, 3501
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Ji (2020) Int. J. Mol. Med. Genome-wide DNA methylation regulation analysis of long non-coding RNAs in glioblastoma 46, 224
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Urdiciain (2020) Int. J. Oncol. The synergistic effect of DZ-NEP, panobinostat and temozolomide reduces clonogenicity and induces apoptosis in glioblastoma cells 56, 283
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