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Luckman, Steven P., Coxon, Fraser P., Ebetino, Frank H., Russell, R. Graham G., Rogers, Michael J. (1998) Heterocycle-Containing Bisphosphonates Cause Apoptosis and Inhibit Bone Resorption by Preventing Protein Prenylation: Evidence from Structure-Activity Relationships in J774 Macrophages. Journal of Bone and Mineral Research, 13 (11). 1668-1678 doi:10.1359/jbmr.1998.13.11.1668

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Reference TypeJournal (article/letter/editorial)
TitleHeterocycle-Containing Bisphosphonates Cause Apoptosis and Inhibit Bone Resorption by Preventing Protein Prenylation: Evidence from Structure-Activity Relationships in J774 Macrophages
JournalJournal of Bone and Mineral Research
AuthorsLuckman, Steven P.Author
Coxon, Fraser P.Author
Ebetino, Frank H.Author
Russell, R. Graham G.Author
Rogers, Michael J.Author
Year1998 (November 1)Volume13
Issue11
PublisherWiley
DOIdoi:10.1359/jbmr.1998.13.11.1668Search in ResearchGate
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Mindat Ref. ID7723213Long-form Identifiermindat:1:5:7723213:7
GUID0
Full ReferenceLuckman, Steven P., Coxon, Fraser P., Ebetino, Frank H., Russell, R. Graham G., Rogers, Michael J. (1998) Heterocycle-Containing Bisphosphonates Cause Apoptosis and Inhibit Bone Resorption by Preventing Protein Prenylation: Evidence from Structure-Activity Relationships in J774 Macrophages. Journal of Bone and Mineral Research, 13 (11). 1668-1678 doi:10.1359/jbmr.1998.13.11.1668
Plain TextLuckman, Steven P., Coxon, Fraser P., Ebetino, Frank H., Russell, R. Graham G., Rogers, Michael J. (1998) Heterocycle-Containing Bisphosphonates Cause Apoptosis and Inhibit Bone Resorption by Preventing Protein Prenylation: Evidence from Structure-Activity Relationships in J774 Macrophages. Journal of Bone and Mineral Research, 13 (11). 1668-1678 doi:10.1359/jbmr.1998.13.11.1668
In(1998, November) Journal of Bone and Mineral Research Vol. 13 (11) Wiley

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Luckman, Steven P., Hughes, David E., Coxon, Fraser P., Russell, R. Graham G., Rogers, Michael J. (1998) Nitrogen-Containing Bisphosphonates Inhibit the Mevalonate Pathway and Prevent Post-Translational Prenylation of GTP-Binding Proteins, Including Ras. Journal of Bone and Mineral Research, 13 (4). 581-589 doi:10.1359/jbmr.1998.13.4.581
Luckman, Steven P., Hughes, David E., Coxon, Fraser P., Russell, R. Graham G., Rogers, Michael J. (2005) Nitrogen-Containing Biphosphonates Inhibit the Mevalonate Pathway and Prevent Post-Translational Prenylation of GTP-Binding Proteins, Including Ras. Journal of Bone and Mineral Research, 20 (7). 1265-1274 doi:10.1359/jbmr.2005.20.7.1265
Dunford, James E, Rogers, Michael J, Ebetino, Frank H, Phipps, Roger J, Coxon, Fraser P (2006) Inhibition of Protein Prenylation by Bisphosphonates Causes Sustained Activation of Rac, Cdc42, and Rho GTPases. Journal of Bone and Mineral Research, 21 (5). 684-694 doi:10.1359/jbmr.060118
Roelofs, Anke J, Stewart, Charlotte A, Sun, Shuting, Błażewska, Katarzyna M, Kashemirov, Boris A, McKenna, Charles E, Russell, R Graham G, Rogers, Michael J, Lundy, Mark W, Ebetino, Frank H, Coxon, Fraser P (2012) Influence of bone affinity on the skeletal distribution of fluorescently labeled bisphosphonates in vivo. Journal of Bone and Mineral Research, 27 (4). 835-847 doi:10.1002/jbmr.1543
Russell, R. Graham G., Rogers, Michael J., Frith, Julie C., Luckman, Steven P., Coxon, Fraser P., Benford, Helena L., Croucher, Peter I., Shipman, Claire, Fleisch, Herbert A. (1999) The pharmacology of bisphosphonates and new insights into their mechanisms of action. Journal of Bone and Mineral Research, 14. 53-65 doi:10.1002/jbmr.5650140212
Rogers, Michael J., Chilton, Kattya M., Coxon, Fraser P., Lawry, John, Smith, M. Olivia, Suri, Sunita, Russel, R. Graham G. (2009) Bisphosphonates induce apoptosis in mouse macrophage-like cells in vitro by a nitric oxide-independent mechanism. Journal of Bone and Mineral Research, 11 (10). 1482-1491 doi:10.1002/jbmr.5650111015
Coxon, Fraser P., Helfrich, Miep H., Van't Hof, Robert, Sebti, Saïd, Ralston, Stuart H., Hamilton, Andrew, Rogers, Michael J. (2000) Protein Geranylgeranylation Is Required for Osteoclast Formation, Function, and Survival: Inhibition by Bisphosphonates and GGTI-298. Journal of Bone and Mineral Research, 15 (8). 1467-1476 doi:10.1359/jbmr.2000.15.8.1467
Rogers, Michael J., Watts, Donald J., Russell, R. Graham G., Ji, Xiaohui, Xiong, Xiaojuan, Blackburn, G. Michael, Bayless, Allan V., Ebetino, Frank H. (2009) Inhibitory effects of bisphosphonates on growth of amoebae of the cellular slime mold dictyostelium discoideum. Journal of Bone and Mineral Research, 9 (7). 1029-1039 doi:10.1002/jbmr.5650090710
Roelofs, Anke J, Coxon, Fraser P, Ebetino, Frank H, Lundy, Mark W, Henneman, Zachary J, Nancollas, George H, Sun, Shuting, Blazewska, Katarzyna M, Bala, Joy Lynn F, Kashemirov, Boris A, Khalid, Aysha B, McKenna, Charles E, Rogers, Michael J (2010) Fluorescent risedronate analogues reveal bisphosphonate uptake by bone marrow monocytes and localization around osteocytes in vivo. Journal of Bone and Mineral Research, 25 (3). 606-616 doi:10.1359/jbmr.091009
Frith, Julie C., Rogers, Michael J. (2003) Antagonistic Effects of Different Classes of Bisphosphonates in Osteoclasts and Macrophages In Vitro. Journal of Bone and Mineral Research, 18 (2). 204-212 doi:10.1359/jbmr.2003.18.2.204
Van 't Hof, Robert J., Ralston, Stuart H. (1997) Cytokine-Induced Nitric Oxide Inhibits Bone Resorption by Inducing Apoptosis of Osteoclast Progenitors and Suppressing Osteoclast Activity. Journal of Bone and Mineral Research, 12 (11). 1797-1804 doi:10.1359/jbmr.1997.12.11.1797
 
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