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Wu, X., Senechal, K., Neshat, M. S., Whang, Y. E., Sawyers, C. L. (1998) The PTEN/MMAC1 tumor suppressor phosphatase functions as a negative regulator of the phosphoinositide 3-kinase/Akt pathway. Proceedings of the National Academy of Sciences, 95 (26) 15587-15591 doi:10.1073/pnas.95.26.15587

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Reference TypeJournal (article/letter/editorial)
TitleThe PTEN/MMAC1 tumor suppressor phosphatase functions as a negative regulator of the phosphoinositide 3-kinase/Akt pathway
JournalProceedings of the National Academy of Sciences
AuthorsWu, X.Author
Senechal, K.Author
Neshat, M. S.Author
Whang, Y. E.Author
Sawyers, C. L.Author
Year1998 (December 22)Volume95
Issue26
PublisherProceedings of the National Academy of Sciences
DOIdoi:10.1073/pnas.95.26.15587Search in ResearchGate
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Mindat Ref. ID1616279Long-form Identifiermindat:1:5:1616279:4
GUID0
Full ReferenceWu, X., Senechal, K., Neshat, M. S., Whang, Y. E., Sawyers, C. L. (1998) The PTEN/MMAC1 tumor suppressor phosphatase functions as a negative regulator of the phosphoinositide 3-kinase/Akt pathway. Proceedings of the National Academy of Sciences, 95 (26) 15587-15591 doi:10.1073/pnas.95.26.15587
Plain TextWu, X., Senechal, K., Neshat, M. S., Whang, Y. E., Sawyers, C. L. (1998) The PTEN/MMAC1 tumor suppressor phosphatase functions as a negative regulator of the phosphoinositide 3-kinase/Akt pathway. Proceedings of the National Academy of Sciences, 95 (26) 15587-15591 doi:10.1073/pnas.95.26.15587
In(1998, December) Proceedings of the National Academy of Sciences Vol. 95 (26) Proceedings of the National Academy of Sciences

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Whang, Y. E., Wu, X., Suzuki, H., Reiter, R. E., Tran, C., Vessella, R. L., Said, J. W., Isaacs, W. B., Sawyers, C. L. (1998) Inactivation of the tumor suppressor PTEN/MMAC1 in advanced human prostate cancer through loss of expression. Proceedings of the National Academy of Sciences, 95 (9) 5246-5250 doi:10.1073/pnas.95.9.5246
Cantley, L. C., Neel, B. G. (1999) New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway. Proceedings of the National Academy of Sciences, 96 (8) 4240-4245 doi:10.1073/pnas.96.8.4240
Wu, X., Hepner, K., Castelino-Prabhu, S., Do, D., Kaye, M. B., Yuan, X.-J., Wood, J., Ross, C., Sawyers, C. L., Whang, Y. E. (2000) Evidence for regulation of the PTEN tumor suppressor by a membrane-localized multi-PDZ domain containing scaffold protein MAGI-2. Proceedings of the National Academy of Sciences, 97 (8) 4233-4238 doi:10.1073/pnas.97.8.4233
Delcommenne, M., Tan, C., Gray, V., Rue, L., Woodgett, J., Dedhar, S. (1998) Phosphoinositide-3-OH kinase-dependent regulation of glycogen synthase kinase 3 and protein kinase B/AKT by the integrin-linked kinase. Proceedings of the National Academy of Sciences, 95 (19) 11211-11216 doi:10.1073/pnas.95.19.11211
Meskiene, I., Bogre, L., Glaser, W., Balog, J., Brandstotter, M., Zwerger, K., Ammerer, G., Hirt, H. (1998) MP2C, a plant protein phosphatase 2C, functions as a negative regulator of mitogen-activated protein kinase pathways in yeast and plants. Proceedings of the National Academy of Sciences, 95 (4) 1938-1943 doi:10.1073/pnas.95.4.1938
Ramaswamy, S., Nakamura, N., Vazquez, F., Batt, D. B., Perera, S., Roberts, T. M., Sellers, W. R. (1999) Regulation of G1 progression by the PTEN tumor suppressor protein is linked to inhibition of the phosphatidylinositol 3-kinase/Akt pathway. Proceedings of the National Academy of Sciences, 96 (5) 2110-2115 doi:10.1073/pnas.96.5.2110
Li, D.-M., Sun, H. (1998) PTEN/MMAC1/TEP1 suppresses the tumorigenicity and induces G1 cell cycle arrest in human glioblastoma cells. Proceedings of the National Academy of Sciences, 95 (26) 15406-15411 doi:10.1073/pnas.95.26.15406
Akagi, T., Shishido, T., Murata, K., Hanafusa, H. (2000) v-Crk activates the phosphoinositide 3-kinase/AKT pathway in transformation. Proceedings of the National Academy of Sciences, 97 (13) 7290-7295 doi:10.1073/pnas.140210297
Neshat, M. S., Mellinghoff, I. K., Tran, C., Stiles, B., Thomas, G., Petersen, R., Frost, P., Gibbons, J. J., Wu, H., Sawyers, C. L. (2001) Enhanced sensitivity of PTEN-deficient tumors to inhibition of FRAP/mTOR. Proceedings of the National Academy of Sciences, 98 (18) 10314-10319 doi:10.1073/pnas.171076798
Cheng, X., Ma, Y., Moore, M., Hemmings, B. A., Taylor, S. S. (1998) Phosphorylation and activation of cAMP-dependent protein kinase by phosphoinositide-dependent protein kinase. Proceedings of the National Academy of Sciences, 95 (17) 9849-9854 doi:10.1073/pnas.95.17.9849
Gil, E. B., Malone Link, E., Liu, L. X., Johnson, C. D., Lees, J. A. (1999) Regulation of the insulin-like developmental pathway of Caenorhabditis elegans by a homolog of the PTEN tumor suppressor gene. Proceedings of the National Academy of Sciences, 96 (6) 2925-2930 doi:10.1073/pnas.96.6.2925
 
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