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Cantley, L. C., Neel, B. G. (1999) New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway. Proceedings of the National Academy of Sciences, 96 (8) 4240-4245 doi:10.1073/pnas.96.8.4240

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Reference TypeJournal (article/letter/editorial)
TitleNew insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway
JournalProceedings of the National Academy of Sciences
AuthorsCantley, L. C.Author
Neel, B. G.Author
Year1999 (April 13)Volume96
Issue8
PublisherProceedings of the National Academy of Sciences
DOIdoi:10.1073/pnas.96.8.4240Search in ResearchGate
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Mindat Ref. ID1637667Long-form Identifiermindat:1:5:1637667:0
GUID0
Full ReferenceCantley, L. C., Neel, B. G. (1999) New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway. Proceedings of the National Academy of Sciences, 96 (8) 4240-4245 doi:10.1073/pnas.96.8.4240
Plain TextCantley, L. C., Neel, B. G. (1999) New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway. Proceedings of the National Academy of Sciences, 96 (8) 4240-4245 doi:10.1073/pnas.96.8.4240
In(1999, April) Proceedings of the National Academy of Sciences Vol. 96 (8) Proceedings of the National Academy of Sciences

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Wu, X., Senechal, K., Neshat, M. S., Whang, Y. E., Sawyers, C. L. (1998) The PTEN/MMAC1 tumor suppressor phosphatase functions as a negative regulator of the phosphoinositide 3-kinase/Akt pathway. Proceedings of the National Academy of Sciences, 95 (26) 15587-15591 doi:10.1073/pnas.95.26.15587
Ramaswamy, S., Nakamura, N., Vazquez, F., Batt, D. B., Perera, S., Roberts, T. M., Sellers, W. R. (1999) Regulation of G1 progression by the PTEN tumor suppressor protein is linked to inhibition of the phosphatidylinositol 3-kinase/Akt pathway. Proceedings of the National Academy of Sciences, 96 (5) 2110-2115 doi:10.1073/pnas.96.5.2110
Taniguchi, C. M., Tran, T. T., Kondo, T., Luo, J., Ueki, K., Cantley, L. C., Kahn, C. R. (2006) Phosphoinositide 3-kinase regulatory subunit p85  suppresses insulin action via positive regulation of PTEN. Proceedings of the National Academy of Sciences, 103 (32) 12093-12097 doi:10.1073/pnas.0604628103
Luo, J., Sobkiw, C. L., Logsdon, N. M., Watt, J. M., Signoretti, S., O'Connell, F., Shin, E., Shim, Y., Pao, L., Neel, B. G., DePinho, R. A., Loda, M., Cantley, L. C. (2005) Modulation of epithelial neoplasia and lymphoid hyperplasia in PTEN+/- mice by the p85 regulatory subunits of phosphoinositide 3-kinase. Proceedings of the National Academy of Sciences, 102 (29) 10238-10243 doi:10.1073/pnas.0504378102
Clurman, B. E., Porter, P. (1998) New insights into the tumor suppression function of P27Kip1. Proceedings of the National Academy of Sciences, 95 (26) 15158-15160 doi:10.1073/pnas.95.26.15158
(2016) Correction for Taniguchi et al., Phosphoinositide 3-kinase regulatory subunit p85α suppresses insulin action via positive regulation of PTEN. Proceedings of the National Academy of Sciences, 113 (25) doi:10.1073/pnas.1607478113
Ozes, O. N., Akca, H., Mayo, L. D., Gustin, J. A., Maehama, T., Dixon, J. E., Donner, D. B. (2001) A phosphatidylinositol 3-kinase/Akt/mTOR pathway mediates and PTEN antagonizes tumor necrosis factor inhibition of insulin signaling through insulin receptor substrate-1. Proceedings of the National Academy of Sciences, 98 (8) 4640-4645 doi:10.1073/pnas.051042298
Gil, E. B., Malone Link, E., Liu, L. X., Johnson, C. D., Lees, J. A. (1999) Regulation of the insulin-like developmental pathway of Caenorhabditis elegans by a homolog of the PTEN tumor suppressor gene. Proceedings of the National Academy of Sciences, 96 (6) 2925-2930 doi:10.1073/pnas.96.6.2925
Mihaylova, V. T., Borland, C. Z., Manjarrez, L., Stern, M. J., Sun, H. (1999) The PTEN tumor suppressor homolog in Caenorhabditis elegans regulates longevity and dauer formation in an insulin receptor-like signaling pathway. Proceedings of the National Academy of Sciences, 96 (13) 7427-7432 doi:10.1073/pnas.96.13.7427
Fan, R., Kim, N.-G., Gumbiner, B. M. (2013) Regulation of Hippo pathway by mitogenic growth factors via phosphoinositide 3-kinase and phosphoinositide-dependent kinase-1. Proceedings of the National Academy of Sciences, 110 (7) 2569-2574 doi:10.1073/pnas.1216462110
Zhang, W.-J., Wei, H., Hagen, T., Frei, B. (2007)  -Lipoic acid attenuates LPS-induced inflammatory responses by activating the phosphoinositide 3-kinase/Akt signaling pathway. Proceedings of the National Academy of Sciences, 104 (10) 4077-4082 doi:10.1073/pnas.0700305104
 
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